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Therapeutic potential of mesenchymal stromal/stem cells in critical-care patients with systemic inflammatory response syndrome

Ziegler K, Kerimi A, Poquet L, Williamson G

By facilitating the removal of toxins, pollutants, and metabolic waste products, glutathione helps to lighten the burden on the immune system, allowing it to focus its resources on fighting infections and maintaining overall health

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The declining plasma concentration provides a quantitative framework for researchers designing dose-response studies, as physiologically relevant in vitro concentrations should bracket the 200-500 nM range to model the young-to-aged spectrum